Publications eligible for electronic reprint

This section features permalinks to publications eligible for a free-access electronic reprint service by the journal.

List of Publications

Taubenschmid-Stowers, J., Orthofer, M., Laemmerer, A (...) Horn, M., Penninger, JM. (2023). A whole-genome scan for Artemisinin cytotoxicity reveals a novel therapy for human brain tumors. EMBO Mol Med. 15(3):e16959

Sidhaye, J., Trepte, P., Sepke, N (...) Mechtler, K., Knoblich, JA. (2023). Integrated transcriptome and proteome analysis reveals posttranscriptional regulation of ribosomal genes in human brain organoids. Elife. 12

Ritzau-Reid, KI., Callens, SJP., Xie, R (...) Knoblich, JA., Stevens, MM. (2023). Microfibrous Scaffolds Guide Stem Cell Lumenogenesis and Brain Organoid Engineering. Adv Mater. :e2300305

Li, C., Fleck, JS., Martins-Costa, C (...) Treutlein, B., Knoblich, JA. (2023). Single-cell brain organoid screening identifies developmental defects in autism. Nature. 621(7978):373-380

Martins-Costa, C., Pham, VA., Sidhaye, J (...) Corsini, NS., Knoblich, JA. (2023). Morphogenesis and development of human telencephalic organoids in the absence and presence of exogenous extracellular matrix. EMBO J. :e113213

Reumann, D., Krauditsch, C., Novatchkova, M (...) Parmar, M., Knoblich, JA. (2023). In vitro modeling of the human dopaminergic system using spatially arranged ventral midbrain-striatum-cortex assembloids. Nat Methods. 20(12):2034-2047

Pașca, SP., Arlotta, P., Bateup, HS (...) Treutlein, B., Vaccarino, FM. (2022). A nomenclature consensus for nervous system organoids and assembloids. Nature. 609(7929):907-910

Corsini, NS., Knoblich, JA. (2022). Human organoids: New strategies and methods for analyzing human development and disease. Cell. 185(15):2756-2769

Eichmüller, OL., Corsini, NS., Vértesy, Á (...) Feucht, M., Knoblich, JA. (2022). Amplification of human interneuron progenitors promotes brain tumors and neurological defects. Science. 375(6579):eabf5546

Vértesy, Á., Eichmüller, OL., Naas, J (...) von Haeseler, A., Knoblich, JA. (2022). Gruffi: an algorithm for computational removal of stressed cells from brain organoid transcriptomic datasets. EMBO J. :e111118

Eichmüller, OL., Knoblich, JA. (2022). Human cerebral organoids - a new tool for clinical neurology research. Nat Rev Neurol.

Hagelkruys, A., Horrer, M., Taubenschmid-Stowers, J (...) Knoblich, JA., Penninger, JM. (2022). The HUSH complex controls brain architecture and protocadherin fidelity. Sci Adv. 8(44):eabo7247

Bajaj, S., Bagley, JA., Sommer, C (...) Lévi-Strauss, J., Knoblich, JA. (2021). Neurotransmitter signaling regulates distinct phases of multimodal human interneuron migration. EMBO J. :e108714

Bock, C., Boutros, M., Camp, JG (...) Treutlein, B., Vries, RGJ. (2021). The Organoid Cell Atlas. Nat Biotechnol. 39(1):13-17

Hyun, I., Clayton, EW., Cong, Y (...) Takahashi, J., Knoblich, JA. (2021). ISSCR guidelines for the transfer of human pluripotent stem cells and their direct derivatives into animal hosts. Stem Cell Reports. 16(6):1409-1415

Lovell-Badge, R., Anthony, E., Barker, RA (...) Zettler, PJ., Zhai, X. (2021). ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update. Stem Cell Reports. 16(6):1398-1408

Krenn, V., Bosone, C., Burkard, TR (...) Mirazimi, A., Knoblich, JA. (2021). Organoid modeling of Zika and herpes simplex virus 1 infections reveals virus-specific responses leading to microcephaly. Cell Stem Cell. 28(8):1362-1379.e7

Rajewsky, N., Almouzni, G., Gorski, SA (...) Vidal, M., Voet, T. (2021). Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine. Nature. 592(7852):E8

Sidhaye, J., Knoblich, JA. (2021). Brain organoids: an ensemble of bioassays to investigate human neurodevelopment and disease. Cell Death Differ. 28(1):52-67

Landskron, L., Bonnay, F., Burkard, TR., Knoblich, JA. (2020). DigiTAG-a RNA Sequencing Approach to Analyze Transcriptomes of Rare Cell Populations in <i>Drosophila melanogaster</i>. Bio Protoc. 10(21):e3809

Bonnay, F., Knoblich, JA. (2020). Prospero Phase-Separating the Way to Neuronal Differentiation. Dev Cell. 52(3):251-252

Esk, C., Lindenhofer, D., Haendeler, S (...) von Haeseler, A., Knoblich, JA. (2020). A human tissue screen identifies a regulator of ER secretion as a brain-size determinant. Science. 370(6519):935-941

Oliver L. Eichmüller, Nina S. Corsini, Ábel Vértesy, Theresa Scholl, Victoria-Elisabeth Gruber, Angela M. Peer, Julia Chu, Maria Novatchkova, Mercedes F. Paredes, Martha Feucht, Jürgen A. Knoblich (2020). Cerebral organoid model reveals excessive proliferation of human caudal late interneuron progenitors in Tuberous Sclerosis Complex BioRxiv.

Bonnay, F., Veloso, A., Steinmann, V (...) Zinzen, RP., Knoblich, JA. (2020). Oxidative Metabolism Drives Immortalization of Neural Stem Cells during Tumorigenesis. Cell. 182(6):1490-1507.e19

Kim, J., Koo, BK., Knoblich, JA. (2020). Human organoids: model systems for human biology and medicine. Nat Rev Mol Cell Biol. 21(10):571-584

Rajewsky, N., Almouzni, G., Gorski, SA (...) Vidal, M., Voet, T. (2020). LifeTime and improving European healthcare through cell-based interceptive medicine. Nature. 587(7834):377-386

Bassett, DS., Cullen, KE., Eickhoff, SB (...) Sur, M., Ueda, HR. (2020). Reflections on the past two decades of neuroscience. Nat Rev Neurosci. 21(10):524-534

Lehmann, R., Lee, CM., Shugart, EC (...) Nelson, CM., Wilson, KM. (2019). Human organoids: a new dimension in cell biology. Mol Biol Cell. 30(10):1129-1137

Abdusselamoglu, MD., Landskron, L., Bowman, SK (...) Kingston, RE., Knoblich, JA. (2019). Dynamics of activating and repressive histone modifications in <i>Drosophila</i> neural stem cell lineages and brain tumors. Development. 146(23)

Abdusselamoglu, MD., Eroglu, E., Burkard, TR., Knoblich, JA. (2019). The transcription factor odd-paired regulates temporal identity in transit-amplifying neural progenitors via an incoherent feed-forward loop. Elife. 8

Masselink, W., Reumann, D., Murawala, P (...) Knoblich, JA., Tanaka, EM. (2019). Broad applicability of a streamlined ethyl cinnamate-based clearing procedure. Development. 146(3)

Wimmer, RA., Leopoldi, A., Aichinger, M (...) Kerjaschki, D., Penninger, JM. (2019). Human blood vessel organoids as a model of diabetic vasculopathy. Nature. 565(7740):505-510

Corsini, NS., Knoblich, JA. (2018). Tracing Stem Cell Division in Adult Neurogenesis. Cell Stem Cell. 22(2):143-145

Corsini, NS., Peer, AM., Moeseneder, P (...) Moll, I., Knoblich, JA. (2018). Coordinated Control of mRNA and rRNA Processing Controls Embryonic Stem Cell Pluripotency and Differentiation. Cell Stem Cell. 22(4):543-558.e12

Wissel, S., Harzer, H., Bonnay, F (...) Neumüller, RA., Knoblich, JA. (2018). Time-resolved transcriptomics in neural stem cells identifies a v-ATPase/Notch regulatory loop. J Cell Biol. 217(9):3285-3300

Bian, S., Repic, M., Guo, Z (...) Krauditsch, C., Knoblich, JA. (2018). Author Correction: Genetically engineered cerebral organoids model brain tumor formation. Nat Methods. 15(9):748

Landskron, L., Steinmann, V., Bonnay, F (...) Reichert, H., Knoblich, JA. (2018). The asymmetrically segregating lncRNA cherub is required for transforming stem cells into malignant cells. Elife. 7

Lancaster, MA., Corsini, NS., Wolfinger, S (...) Livesey, FJ., Knoblich, JA. (2018). Publisher Correction: Guided self-organization and cortical plate formation in human brain organoids. Nat Biotechnol. 36(10):1016

Bian, S., Repic, M., Guo, Z (...) Krauditsch, C., Knoblich, JA. (2018). Genetically engineered cerebral organoids model brain tumor formation. Nat Methods. 15(8):631-639

Reichardt, I., Bonnay, F., Steinmann, V (...) Meister, G., Knoblich, JA. (2018). The tumor suppressor Brat controls neuronal stem cell lineages by inhibiting Deadpan and Zelda. EMBO Rep. 19(1):102-117

Falk, S., Bugeon, S., Ninkovic, J (...) Knoblich, JA., Götz, M. (2017). Time-Specific Effects of Spindle Positioning on Embryonic Progenitor Pool Composition and Adult Neural Stem Cell Seeding. Neuron. 93(4):777-791.e3

Huch, M., Knoblich, JA., Lutolf, MP., Martinez-Arias, A. (2017). The hope and the hype of organoid research. Development. 144(6):938-941

Bagley, JA., Reumann, D., Bian, S., Lévi-Strauss, J., Knoblich, JA. (2017). Fused cerebral organoids model interactions between brain regions. Nat Methods. 14(7):743-751

Bredenoord, AL., Clevers, H., Knoblich, JA. (2017). Human tissues in a dish: The research and ethical implications of organoid technology. Science. 355(6322)

Li, Y., Muffat, J., Omer, A (...) Knoblich, JA., Jaenisch, R. (2017). Induction of Expansion and Folding in Human Cerebral Organoids. Cell Stem Cell. 20(3):385-396.e3

Abramczuk, MK., Burkard, TR., Rolland, V (...) Reichert, H., Knoblich, JA. (2017). The splicing co-factor Barricade/Tat-SF1 is required for cell cycle and lineage progression in <i>Drosophila</i> neural stem cells. Development. 144(21):3932-3945

Lancaster, MA., Corsini, NS., Wolfinger, S (...) Livesey, FJ., Knoblich, JA. (2017). Guided self-organization and cortical plate formation in human brain organoids. Nat Biotechnol. 35(7):659-666

Renner, M., Lancaster, MA., Bian, S (...) Chung, K., Knoblich, JA. (2017). Self-organized developmental patterning and differentiation in cerebral organoids. EMBO J. 36(10):1316-1329

Luo, C., Lancaster, MA., Castanon, R (...) Knoblich, JA., Ecker, JR. (2016). Cerebral Organoids Recapitulate Epigenomic Signatures of the Human Fetal Brain. Cell Rep. 17(12):3369-3384

Knoblich, JA. (2016). Lab-Built Brains. Sci Am. 316(1):26-31

Fededa, JP., Esk, C., Mierzwa, B (...) Knoblich, JA., Gerlich, DW. (2016). MicroRNA-34/449 controls mitotic spindle orientation during mammalian cortex development. EMBO J. 35(22):2386-2398

Landskron, L., Knoblich, JA. (2016). You Are What You Eat: Linking Metabolic Asymmetry and Cell Fate Choice. Dev Cell. 37(3):206-8

Wissel, S., Kieser, A., Yasugi, T (...) Knoblich, JA., Neumüller, RA. (2016). A Combination of CRISPR/Cas9 and Standardized RNAi as a Versatile Platform for the Characterization of Gene Function. G3 (Bethesda). 6(8):2467-78

Homem, CC., Repic, M., Knoblich, JA. (2015). Proliferation control in neural stem and progenitor cells. Nat Rev Neurosci. 16(11):647-59

Akbari, OS., Bellen, HJ., Bier, E (...) Ueda, R., Wildonger, J. (2015). BIOSAFETY. Safeguarding gene drive experiments in the laboratory. Science. 349(6251):927-9

Ballard, MS., Zhu, A., Iwai, N (...) Knoblich, JA., Hinck, L. (2015). Mammary Stem Cell Self-Renewal Is Regulated by Slit2/Robo1 Signaling through SNAI1 and mINSC. Cell Rep. 13(2):290-301

Camp, JG., Badsha, F., Florio, M (...) Huttner, WB., Treutlein, B. (2015). Human cerebral organoids recapitulate gene expression programs of fetal neocortex development. Proc Natl Acad Sci U S A. 112(51):15672-7

Hagelkruys, A., Lagger, S., Krahmer, J (...) Knoblich, JA., Seiser, C. (2014). A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog. Development. 141(3):604-616

Lancaster, MA., Knoblich, JA. (2014). Generation of cerebral organoids from human pluripotent stem cells. Nat Protoc. 9(10):2329-40

Lancaster, MA., Knoblich, JA. (2014). Organogenesis in a dish: modeling development and disease using organoid technologies. Science. 345(6194):1247125

Homem, CCF., Steinmann, V., Burkard, TR (...) Esterbauer, H., Knoblich, JA. (2014). Ecdysone and mediator change energy metabolism to terminate proliferation in Drosophila neural stem cells. Cell. 158(4):874-888

Marchetti, G., Reichardt, I., Knoblich, JA., Besse, F. (2014). The TRIM-NHL protein Brat promotes axon maintenance by repressing src64B expression. J Neurosci. 34(41):13855-64

Ayukawa, T., Akiyama, M., Mummery-Widmer, JL (...) Sasaki, T., Yamazaki, M. (2014). Dachsous-dependent asymmetric localization of spiny-legs determines planar cell polarity orientation in Drosophila. Cell Rep. 8(2):610-21

Yasugi, T., Fischer, A., Jiang, Y., Reichert, H., Knoblich, JA. (2014). A regulatory transcriptional loop controls proliferation and differentiation in Drosophila neural stem cells. PLoS One. 9(5):e97034

Mauri, F., Reichardt, I., Mummery-Widmer, JL., Yamazaki, M., Knoblich, JA. (2014). The conserved discs-large binding partner Banderuola regulates asymmetric cell division in Drosophila. Curr Biol. 24(16):1811-25

Williams, SE., Ratliff, LA., Postiglione, MP., Knoblich, JA., Fuchs, E. (2014). Par3-mInsc and Gαi3 cooperate to promote oriented epidermal cell divisions through LGN. Nat Cell Biol. 16(8):758-69

Eroglu, E., Burkard, TR., Jiang, Y (...) Reichert, H., Knoblich, JA. (2014). SWI/SNF complex prevents lineage reversion and induces temporal patterning in neural stem cells. Cell. 156(6):1259-1273

Jüschke, C., Xie, Y., Postiglione, MP., Knoblich, JA. (2014). Analysis and modeling of mitotic spindle orientations in three dimensions. Proc Natl Acad Sci U S A. 111(3):1014-9

Xie, Y., Jüschke, C., Esk, C., Hirotsune, S., Knoblich, JA. (2013). The phosphatase PP4c controls spindle orientation to maintain proliferative symmetric divisions in the developing neocortex. Neuron. 79(2):254-65

Sparmann, A., Xie, Y., Verhoeven, E (...) Knoblich, JA., van Lohuizen, M. (2013). The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation. EMBO J. 32(11):1598-612

Reichardt, I., Knoblich, JA. (2013). Cell biology: Notch recycling is numbed. Curr Biol. 23(7):R270-2

Bardet, AF., Steinmann, J., Bafna, S (...) Zeitlinger, J., Stark, A. (2013). Identification of transcription factor binding sites from ChIP-seq data at high resolution. Bioinformatics. 29(21):2705-13

Jüschke, C., Dohnal, I., Pichler, P (...) Mechtler, K., Knoblich, JA. (2013). Transcriptome and proteome quantification of a tumor model provides novel insights into post-transcriptional gene regulation. Genome Biol. 14(11):r133

Homem, CC., Reichardt, I., Berger, C., Lendl, T., Knoblich, JA. (2013). Long-term live cell imaging and automated 4D analysis of drosophila neuroblast lineages. PLoS One. 8(11):e79588

Lancaster, MA., Renner, M., Martin, CA (...) Jackson, AP., Knoblich, JA. (2013). Cerebral organoids model human brain development and microcephaly. Nature. 501(7467):373-9

Harzer, H., Berger, C., Conder, R., Schmauss, G., Knoblich, JA. (2013). FACS purification of Drosophila larval neuroblasts for next-generation sequencing. Nat Protoc. 8(6):1088-1099

Homem, CC., Knoblich, JA. (2012). Drosophila neuroblasts: a model for stem cell biology. Development. 139(23):4297-310

Goulas, S., Conder, R., Knoblich, JA. (2012). The Par complex and integrins direct asymmetric cell division in adult intestinal stem cells. Cell Stem Cell. 11(4):529-40

Lancaster, MA., Knoblich, JA. (2012). Spindle orientation in mammalian cerebral cortical development. Curr Opin Neurobiol. 22(5):737-46

Berger, C., Harzer, H., Burkard, TR (...) Reichert, H., Knoblich, JA. (2012). FACS purification and transcriptome analysis of drosophila neural stem cells reveals a role for Klumpfuss in self-renewal. Cell Rep. 2(2):407-18

Khazaei, MR., Bunk, EC., Hillje, AL (...) Young, P., Schwamborn, JC. (2011). The E3-ubiquitin ligase TRIM2 regulates neuronal polarization. J Neurochem. 117(1):29-37

Postiglione, MP., Jüschke, C., Xie, Y (...) Charalambous, C., Knoblich, JA. (2011). Mouse inscuteable induces apical-basal spindle orientation to facilitate intermediate progenitor generation in the developing neocortex. Neuron. 72(2):269-84

Richter, C., Oktaba, K., Steinmann, J., Müller, J., Knoblich, JA. (2011). The tumour suppressor L(3)mbt inhibits neuroepithelial proliferation and acts on insulator elements. Nat Cell Biol. 13(9):1029-39

Neumüller, RA., Richter, C., Fischer, A (...) Neumüller, KG., Knoblich, JA. (2011). Genome-wide analysis of self-renewal in Drosophila neural stem cells by transgenic RNAi. Cell Stem Cell. 8(5):580-93

Knoblich, JA. (2010). Asymmetric cell division: recent developments and their implications for tumour biology. Nat Rev Mol Cell Biol. 11(12):849-60

Neumüller, RA., Knoblich, JA. (2009). Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer. Genes Dev. 23(23):2675-99

Schwamborn, JC., Berezikov, E., Knoblich, JA. (2009). The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors. Cell. 136(5):913-25

Coumailleau, F., Fürthauer, M., Knoblich, JA., González-Gaitán, M. (2009). Directional Delta and Notch trafficking in Sara endosomes during asymmetric cell division. Nature. 458(7241):1051-5

Mummery-Widmer, JL., Yamazaki, M., Stoeger, T (...) Dickson, BJ., Knoblich, JA. (2009). Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi. Nature. 458(7241):987-92

Neumüller, RA., Knoblich, JA. (2009). Wicked views on stem cell news. Nat Cell Biol. 11(6):678-9

Conder, R., Knoblich, JA. (2009). Fly stem cell research gets infectious. Cell. 137(7):1185-7

Speicher, S., Fischer, A., Knoblich, J., Carmena, A. (2008). The PDZ protein Canoe regulates the asymmetric division of Drosophila neuroblasts and muscle progenitors. Curr Biol. 18(11):831-7

Schwamborn, JC., Knoblich, JA. (2008). LIS1 and spindle orientation in neuroepithelial cells. Cell Stem Cell. 2(3):193-4

Knoblich, JA. (2008). Mechanisms of asymmetric stem cell division. Cell. 132(4):583-97

Jüschke, C., Knoblich, JA. (2008). Purification of Drosophila protein complexes for mass spectrometry. Methods Mol Biol. 420:347-58

Benetka, W., Mehlmer, N., Maurer-Stroh, S (...) Teige, M., Eisenhaber, F. (2008). Experimental testing of predicted myristoylation targets involved in asymmetric cell division and calcium-dependent signalling. Cell Cycle. 7(23):3709-19

Barral, Y., Knoblich, J. (2008). Cell division, growth and death. Curr Opin Cell Biol. 20(6):647-9

Wirtz-Peitz, F., Nishimura, T., Knoblich, JA. (2008). Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization. Cell. 135(1):161-73

Neumüller, RA., Betschinger, J., Fischer, A (...) Cohen, SM., Knoblich, JA. (2008). Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage. Nature. 454(7201):241-5

Bowman, SK., Rolland, V., Betschinger, J (...) Emery, G., Knoblich, JA. (2008). The tumor suppressors Brat and Numb regulate transit-amplifying neuroblast lineages in Drosophila. Dev Cell. 14(4):535-46

Knoblich, J. (2007). On the backroads to cellular asymmetry. Development (Cambridge, England). 134(24):4311-3

Knoblich, JA. (2006). Cell biology. Sara splits the signal. Science. 314(5802):1094-6

Emery, G., Knoblich, JA. (2006). Endosome dynamics during development. Curr Opin Cell Biol. 18(4):407-15

Wirtz-Peitz, F., Knoblich, JA. (2006). Lethal giant larvae take on a life of their own. Trends Cell Biol. 16(5):234-41

Betschinger, J., Mechtler, K., Knoblich, JA. (2006). Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells. Cell. 124(6):1241-53

Gallagher, CM., Knoblich, JA. (2006). The conserved c2 domain protein lethal (2) giant discs regulates protein trafficking in Drosophila. Dev Cell. 11(5):641-53

Bowman, SK., Neumüller, RA., Novatchkova, M., Du, Q., Knoblich, JA. (2006). The Drosophila NuMA Homolog Mud regulates spindle orientation in asymmetric cell division. Dev Cell. 10(6):731-42

Vishnu, S., Hertenstein, A., Betschinger, J (...) Gert de Couet, H., Fischbach, KF. (2006). The adaptor protein X11Lalpha/Dmint1 interacts with the PDZ-binding domain of the cell recognition protein Rst in Drosophila. Dev Biol. 289(2):296-307

Hutterer, A., Berdnik, D., Wirtz-Peitz, F (...) Schleiffer, A., Knoblich, JA. (2006). Mitotic activation of the kinase Aurora-A requires its binding partner Bora. Dev Cell. 11(2):147-57

Knoblich, JA. (2005). Pins for spines. Nat Cell Biol. 7(12):1157-8

Zarnescu, DC., Jin, P., Betschinger, J (...) Warren, ST., Moses, K. (2005). Fragile X protein functions with lgl and the par complex in flies and mice. Dev Cell. 8(1):43-52

Jafar-Nejad, H., Andrews, HK., Acar, M (...) Knoblich, JA., Bellen, HJ. (2005). Sec15, a component of the exocyst, promotes notch signaling during the asymmetric division of Drosophila sensory organ precursors. Dev Cell. 9(3):351-63

Knoblich, JA. (2005). Neurobiology: getting axons going. Nature. 436(7051):632-3

Zigman, M., Cayouette, M., Charalambous, C (...) Siderovski, DP., Knoblich, JA. (2005). Mammalian inscuteable regulates spindle orientation and cell fate in the developing retina. Neuron. 48(4):539-45

Bhalerao, S., Berdnik, D., Török, T., Knoblich, JA. (2005). Localization-dependent and -independent roles of numb contribute to cell-fate specification in Drosophila. Curr Biol. 15(17):1583-90

Mayer, B., Emery, G., Berdnik, D., Wirtz-Peitz, F., Knoblich, JA. (2005). Quantitative analysis of protein dynamics during asymmetric cell division. Curr Biol. 15(20):1847-54

Emery, G., Hutterer, A., Berdnik, D (...) Gaitan, MG., Knoblich, JA. (2005). Asymmetric Rab 11 endosomes regulate delta recycling and specify cell fate in the Drosophila nervous system. Cell. 122(5):763-73

Betschinger, J., Eisenhaber, F., Knoblich, JA. (2005). Phosphorylation-induced autoinhibition regulates the cytoskeletal protein Lethal (2) giant larvae. Curr Biol. 15(3):276-82

Hampoelz, B., Hoeller, O., Bowman, SK., Dunican, D., Knoblich, JA. (2005). Drosophila Ric-8 is essential for plasma-membrane localization of heterotrimeric G proteins. Nat Cell Biol. 7(11):1099-105

Hutterer, A., Knoblich, JA. (2005). Numb and alpha-Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs. EMBO Rep. 6(9):836-42

Betschinger, J., Knoblich, JA. (2004). Dare to be different: asymmetric cell division in Drosophila, C. elegans and vertebrates. Curr Biol. 14(16):R674-85

Hampoelz, B., Knoblich, JA. (2004). Heterotrimeric G proteins: new tricks for an old dog. Cell. 119(4):453-6

Hutterer, A., Betschinger, J., Petronczki, M., Knoblich, JA. (2004). Sequential roles of Cdc42, Par-6, aPKC, and Lgl in the establishment of epithelial polarity during Drosophila embryogenesis. Dev Cell. 6(6):845-54

Betschinger, J., Mechtler, K., Knoblich, JA. (2003). The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl. Nature. 422(6929):326-30

Blumer, JB., Bernard, ML., Peterson, YK (...) Knoblich, JA., Lanier, SM. (2003). Interaction of activator of G-protein signaling 3 (AGS3) with LKB1, a serine/threonine kinase involved in cell polarity and cell cycle progression: phosphorylation of the G-protein regulatory (GPR) motif as a regulatory mechanism for the interaction of GPR motifs with Gi alpha. J Biol Chem. 278(26):23217-20

Subramanian, A., Prokop, A., Yamamoto, M (...) Knoblich, JA., Volk, T. (2003). Shortstop recruits EB1/APC1 and promotes microtubule assembly at the muscle-tendon junction. Curr Biol. 13(13):1086-95

Berdnik, D., Török, T., González-Gaitán, M., Knoblich, JA. (2002). The endocytic protein alpha-Adaptin is required for numb-mediated asymmetric cell division in Drosophila. Dev Cell. 3(2):221-31

Tekotte, H., Berdnik, D., Török, T (...) Knoblich, JA., Davis, I. (2002). Dcas is required for importin-alpha3 nuclear export and mechano-sensory organ cell fate specification in Drosophila. Dev Biol. 244(2):396-406

Berdnik, D., Knoblich, JA. (2002). Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis. Curr Biol. 12(8):640-7

Knoblich, JA. (2001). The Drosophila nervous system as a model for asymmetric cell division. Symp Soc Exp Biol. (53):75-89

Schaefer, M., Knoblich, JA. (2001). Protein localization during asymmetric cell division. Exp Cell Res. 271(1):66-74

Knoblich, JA. (2001). Asymmetric cell division during animal development. Nat Rev Mol Cell Biol. 2(1):11-20

Petronczki, M., Knoblich, JA. (2001). DmPAR-6 directs epithelial polarity and asymmetric cell division of neuroblasts in Drosophila. Nat Cell Biol. 3(1):43-9

Bulgheresi, S., Kleiner, E., Knoblich, JA. (2001). Inscuteable-dependent apical localization of the microtubule-binding protein Cornetto suggests a role in asymmetric cell division. J Cell Sci. 114(Pt 20):3655-62

Huynh, JR., Petronczki, M., Knoblich, JA., St Johnston, D. (2001). Bazooka and PAR-6 are required with PAR-1 for the maintenance of oocyte fate in Drosophila. Curr Biol. 11(11):901-6

Schaefer, M., Petronczki, M., Dorner, D., Forte, M., Knoblich, JA. (2001). Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system. Cell. 107(2):183-94

Knoblich, JA. (2000). Epithelial polarity: the ins and outs of the fly epidermis. Curr Biol. 10(21):R791-4

Schaefer, M., Shevchenko, A., Shevchenko, A., Knoblich, JA. (2000). A protein complex containing Inscuteable and the Galpha-binding protein Pins orients asymmetric cell divisions in Drosophila. Curr Biol. 10(7):353-62

Knoblich, JA., Jan, LY., Jan, YN. (1999). Deletion analysis of the Drosophila Inscuteable protein reveals domains for cortical localization and asymmetric localization. Curr Biol. 9(3):155-8

Schober, M., Schaefer, M., Knoblich, JA. (1999). Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts. Nature. 402(6761):548-51

Glotzer, M., Knoblich, JA. (1998). Cell multiplication - editorial overview. Current Opinion in Cell Biology. 10:739-41

Jacobs, HW., Knoblich, JA., Lehner, CF. (1998). Drosophila Cyclin B3 is required for female fertility and is dispensable for mitosis like Cyclin B. Genes Dev. 12(23):3741-51

Shen, CP., Knoblich, JA., Chan, YM (...) Jan, LY., Jan, YN. (1998). Miranda as a multidomain adapter linking apically localized Inscuteable and basally localized Staufen and Prospero during asymmetric cell division in Drosophila. Genes Dev. 12(12):1837-46

Knoblich, JA., Jan, LY., Jan, YN. (1997). Asymmetric segregation of the Drosophila numb protein during mitosis: facts and speculations. Cold Spring Harb Symp Quant Biol. 62:71-7

Knoblich, JA. (1997). Mechanisms of asymmetric cell division during animal development. Curr Opin Cell Biol. 9(6):833-41

Knoblich, JA., Jan, LY., Jan, YN. (1997). The N terminus of the Drosophila Numb protein directs membrane association and actin-dependent asymmetric localization. Proc Natl Acad Sci U S A. 94(24):13005-10

Frise, E., Knoblich, JA., Younger-Shepherd, S., Jan, LY., Jan, YN. (1996). The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage. Proc Natl Acad Sci U S A. 93(21):11925-32

Kraut, R., Chia, W., Jan, LY., Jan, YN., Knoblich, JA. (1996). Role of inscuteable in orienting asymmetric cell divisions in Drosophila. Nature. 383(6595):50-5

Rhyu, MS., Knoblich, JA. (1995). Spindle orientation and asymmetric cell fate. Cell. 82(4):523-6

Sauer, K., Knoblich, JA., Richardson, H., Lehner, CF. (1995). Distinct modes of cyclin E/cdc2c kinase regulation and S-phase control in mitotic and endoreduplication cycles of Drosophila embryogenesis. Genes Dev. 9(11):1327-39

Knoblich, JA., Jan, LY., Jan, YN. (1995). Asymmetric segregation of Numb and Prospero during cell division. Nature. 377(6550):624-7

Kreutzer, MA., Richards, JP., De Silva-Udawatta, MN (...) Lehner, CF., Bennett, KL. (1995). Caenorhabditis elegans cyclin A- and B-type genes: a cyclin A multigene family, an ancestral cyclin B3 and differential germline expression. J Cell Sci. 108 ( Pt 6):2415-24

Knoblich, JA., Sauer, K., Jones, L (...) Saint, R., Lehner, CF. (1994). Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation. Cell. 77(1):107-20

Knoblich, JA., Lehner, CF. (1993). Synergistic action of Drosophila cyclins A and B during the G2-M transition. EMBO J. 12(1):65-74

Lehner, CF., Ried, G., Stern, B., Knoblich, JA. (1992). Cyclins and cdc2 kinases in Drosophila: genetic analyses in a higher eukaryote. Ciba Found Symp. 170:97-109; discussion 110-4