Publications

(2016)
 
Cuylen, S., Blaukopf, C., Politi, AZ., Müller-Reichert, T., Neumann, B., Poser, I., Ellenberg, J., Hyman, AA., Gerlich, DW. (2016). Ki-67 acts as a biological surfactant to disperse mitotic chromosomes. Nature. 535(7611):308-12 (abstract)
 
Fededa, JP., Esk, C., Mierzwa, B., Stanyte, R., Yuan, S., Zheng, H., Ebnet, K., Yan, W., Knoblich, JA., Gerlich, DW. (2016). MicroRNA-34/449 controls mitotic spindle orientation during mammalian cortex development. EMBO J. 35(22):2386-2398 (abstract)
 
S Pedersen, R., Karemore, G., Gudjonsson, T., Rask, MB., Neumann, B., Hériché, JK., Pepperkok, R., Ellenberg, J., Gerlich, DW., Lukas, J., Lukas, C. (2016). Profiling DNA damage response following mitotic perturbations. Nat Commun. 7:13887 (abstract)
 
Uehara, R., Kamasaki, T., Hiruma, S., Poser, I., Yoda, K., Yajima, J., Gerlich, DW., Goshima, G. (2016). Augmin shapes the anaphase spindle for efficient cytokinetic furrow ingression and abscission. Mol Biol Cell. 27(5):812-27 (abstract)
 
(2015)
 
Gentili, C., Castor, D., Kaden, S., Lauterbach, D., Gysi, M., Steigemann, P., Gerlich, DW., Jiricny, J., Ferrari, S. (2015). Chromosome Missegregation Associated with RUVBL1 Deficiency. PLoS One. 10(7):e0133576 (abstract)
 
Lukinavičius, G., Blaukopf, C., Pershagen, E., Schena, A., Reymond, L., Derivery, E., Gonzalez-Gaitan, M., D'Este, E., Hell, SW., Gerlich, DW., Johnsson, K. (2015). SiR-Hoechst is a far-red DNA stain for live-cell nanoscopy. Nat Commun. 6:8497 (abstract)
 
Rudolph, D., Impagnatiello, MA., Blaukopf, C., Sommer, C., Gerlich, DW., Roth, M., Tontsch-Grunt, U., Wernitznig, A., Savarese, F., Hofmann, MH., Albrecht, C., Geiselmann, L., Reschke, M., Garin-Chesa, P., Zuber, J., Moll, J., Adolf, GR., Kraut, N. (2015). Efficacy and mechanism of action of volasertib, a potent and selective inhibitor of Polo-like kinases, in preclinical models of acute myeloid leukemia. J Pharmacol Exp Ther. 352(3):579-89 (abstract)
 
(2014)
 
Lukinavičius, G., Reymond, L., D'Este, E., Masharina, A., Göttfert, F., Ta, H., Güther, A., Fournier, M., Rizzo, S., Waldmann, H., Blaukopf, C., Sommer, C., Gerlich, DW., Arndt, HD., Hell, SW., Johnsson, K. (2014). Fluorogenic probes for live-cell imaging of the cytoskeleton. Nat Methods. 11(7):731-3 (abstract)
 
Mierzwa, B., Gerlich, DW. (2014). Cytokinetic abscission: molecular mechanisms and temporal control. Dev Cell. 31(5):525-38 (abstract)
 
Turgay, Y., Champion, L., Balazs, C., Held, M., Toso, A., Gerlich, DW., Meraldi, P., Kutay, U. (2014). SUN proteins facilitate the removal of membranes from chromatin during nuclear envelope breakdown. J Cell Biol. 204(7):1099-109 (abstract)
 
Vázquez-Novelle, MD., Sansregret, L., Dick, AE., Smith, CA., McAinsh, AD., Gerlich, DW., Petronczki, M. (2014). Cdk1 inactivation terminates mitotic checkpoint surveillance and stabilizes kinetochore attachments in anaphase. Curr Biol. 24(6):638-45 (abstract)
 
(2013)
 
Dick, AE., Gerlich, DW. (2013). Kinetic framework of spindle assembly checkpoint signalling. Nat Cell Biol. 15(11):1370-7 (abstract)
 
Earnshaw, WC., Allshire, RC., Black, BE., Bloom, K., Brinkley, BR., Brown, W., Cheeseman, IM., Choo, KH., Copenhaver, GP., Deluca, JG., Desai, A., Diekmann, S., Erhardt, S., Fitzgerald-Hayes, M., Foltz, D., Fukagawa, T., Gassmann, R., Gerlich, DW., Glover, DM., Gorbsky, GJ., Harrison, SC., Heun, P., Hirota, T., Jansen, LE., Karpen, G., Kops, GJ., Lampson, MA., Lens, SM., Losada, A., Luger, K., Maiato, H., Maddox, PS., Margolis, RL., Masumoto, H., McAinsh, AD., Mellone, BG., Meraldi, P., Musacchio, A., Oegema, K., O'Neill, RJ., Salmon, ED., Scott, KC., Straight, AF., Stukenberg, PT., Sullivan, BA., Sullivan, KF., Sunkel, CE., Swedlow, JR., Walczak, CE., Warburton, PE., Westermann, S., Willard, HF., Wordeman, L., Yanagida, M., Yen, TJ., Yoda, K., Cleveland, DW. (2013). Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant. Chromosome Res. 21(2):101-6 (abstract)
 
Samwer, M., Dehne, HJ., Spira, F., Kollmar, M., Gerlich, DW., Urlaub, H., Görlich, D. (2013). The nuclear F-actin interactome of Xenopus oocytes reveals an actin-bundling kinesin that is essential for meiotic cytokinesis. EMBO J. 32(13):1886-902 (abstract)
 
Sommer, C., Gerlich, DW. (2013). Machine learning in cell biology - teaching computers to recognize phenotypes. J Cell Sci. 126(Pt 24):5529-39 (abstract)
 
Sommer, C., Held, M., Fischer, B., Huber, W., Gerlich, DW. (2013). CellH5: a format for data exchange in high-content screening. Bioinformatics. 29(12):1580-2 (abstract)
 
Uehara, R., Tsukada, Y., Kamasaki, T., Poser, I., Yoda, K., Gerlich, DW., Goshima, G. (2013). Aurora B and Kif2A control microtubule length for assembly of a functional central spindle during anaphase. J Cell Biol. 202(4):623-36 (abstract)
 
(2012)
 
Fededa, JP., Gerlich, DW. (2012). Molecular control of animal cell cytokinesis. Nat Cell Biol. 14(5):440-7 (abstract)
 
Guizetti, J., Gerlich, DW. (2012). ESCRT-III polymers in membrane neck constriction. Trends Cell Biol. 22(3):133-40 (abstract)
 
van der Waal, MS., Saurin, AT., Vromans, MJ., Vleugel, M., Wurzenberger, C., Gerlich, DW., Medema, RH., Kops, GJ., Lens, SM. (2012). Mps1 promotes rapid centromere accumulation of Aurora B. EMBO Rep. 13(9):847-54 (abstract)
 
Wurzenberger, C., Held, M., Lampson, MA., Poser, I., Hyman, AA., Gerlich, DW. (2012). Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores. J Cell Biol. 198(2):173-83 (abstract)
 
Zhong, Q., Busetto, AG., Fededa, JP., Buhmann, JM., Gerlich, DW. (2012). Unsupervised modeling of cell morphology dynamics for time-lapse microscopy. Nat Methods. 9(7):711-3 (abstract)
 
(2011)
 
Dobrynin, G., Popp, O., Romer, T., Bremer, S., Schmitz, MH., Gerlich, DW., Meyer, H. (2011). Cdc48/p97-Ufd1-Npl4 antagonizes Aurora B during chromosome segregation in HeLa cells. J Cell Sci. 124(Pt 9):1571-80 (abstract)
 
Guizetti, J., Schermelleh, L., Mäntler, J., Maar, S., Poser, I., Leonhardt, H., Müller-Reichert, T., Gerlich, DW. (2011). Cortical constriction during abscission involves helices of ESCRT-III-dependent filaments. Science. 331(6024):1616-20 (abstract)
 
Wurzenberger, C., Gerlich, DW. (2011). Phosphatases: providing safe passage through mitotic exit. Nat Rev Mol Cell Biol. 12(8):469-82 (abstract)
 
(2010)
 
Conrad, C., Gerlich, DW. (2010). Automated microscopy for high-content RNAi screening. J Cell Biol. 188(4):453-61 (abstract)
 
Guizetti, J., Gerlich, DW. (2010). Cytokinetic abscission in animal cells. Semin Cell Dev Biol. 21(9):909-16 (abstract)
 
Guizetti, J., Mäntler, J., Müller-Reichert, T., Gerlich, DW. (2010). Correlative time-lapse imaging and electron microscopy to study abscission in HeLa cells. Methods Cell Biol. 96:591-601 (abstract)
 
Held, M., Schmitz, MH., Fischer, B., Walter, T., Neumann, B., Olma, MH., Peter, M., Ellenberg, J., Gerlich, DW. (2010). CellCognition: time-resolved phenotype annotation in high-throughput live cell imaging. Nat Methods. 7(9):747-54 (abstract)
 
Lacroix, B., van Dijk, J., Gold, ND., Guizetti, J., Aldrian-Herrada, G., Rogowski, K., Gerlich, DW., Janke, C. (2010). Tubulin polyglutamylation stimulates spastin-mediated microtubule severing. J Cell Biol. 189(6):945-54 (abstract)
 
Lekomtsev, S., Guizetti, J., Pozniakovsky, A., Gerlich, DW., Petronczki, M. (2010). Evidence that the tumor-suppressor protein BRCA2 does not regulate cytokinesis in human cells. J Cell Sci. 123(Pt 9):1395-400 (abstract)
 
Neumann, B., Walter, T., Hériché, JK., Bulkescher, J., Erfle, H., Conrad, C., Rogers, P., Poser, I., Held, M., Liebel, U., Cetin, C., Sieckmann, F., Pau, G., Kabbe, R., Wünsche, A., Satagopam, V., Schmitz, MH., Chapuis, C., Gerlich, DW., Schneider, R., Eils, R., Huber, W., Peters, JM., Hyman, AA., Durbin, R., Pepperkok, R., Ellenberg, J. (2010). Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes. Nature. 464(7289):721-7 (abstract)
 
Piwko, W., Olma, MH., Held, M., Bianco, JN., Pedrioli, PG., Hofmann, K., Pasero, P., Gerlich, DW., Peter, M. (2010). RNAi-based screening identifies the Mms22L-Nfkbil2 complex as a novel regulator of DNA replication in human cells. EMBO J. 29(24):4210-22 (abstract)
 
Schmitz, MH., Held, M., Janssens, V., Hutchins, JR., Hudecz, O., Ivanova, E., Goris, J., Trinkle-Mulcahy, L., Lamond, AI., Poser, I., Hyman, AA., Mechtler, K., Peters, JM., Gerlich, DW. (2010). Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells. Nat Cell Biol. 12(9):886-93 (abstract)
 
(2009)
 
Bollen, M., Gerlich, DW., Lesage, B. (2009). Mitotic phosphatases: from entry guards to exit guides. Trends Cell Biol. 19(10):531-41 (abstract)
 
Chan, YW., Fava, LL., Uldschmid, A., Schmitz, MH., Gerlich, DW., Nigg, EA., Santamaria, A. (2009). Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly. J Cell Biol. 185(5):859-74 (abstract)
 
Maerki, S., Olma, MH., Staubli, T., Steigemann, P., Gerlich, DW., Quadroni, M., Sumara, I., Peter, M. (2009). The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis. J Cell Biol. 187(6):791-800 (abstract)
 
Neurohr, G., Gerlich, DW. (2009). Assays for mitotic chromosome condensation in live yeast and mammalian cells. Chromosome Res. 17(2):145-54 (abstract)
 
Schmitz, MH., Gerlich, DW. (2009). Automated live microscopy to study mitotic gene function in fluorescent reporter cell lines. Methods Mol Biol. 545:113-34 (abstract)
 
Steigemann, P., Gerlich, DW. (2009). Cytokinetic abscission: cellular dynamics at the midbody. Trends Cell Biol. 19(11):606-16 (abstract)
 
Steigemann, P., Gerlich, DW. (2009). An evolutionary conserved checkpoint controls abscission timing. Cell Cycle. 8(12):1814-5 (abstract)
 
Steigemann, P., Wurzenberger, C., Schmitz, MH., Held, M., Guizetti, J., Maar, S., Gerlich, DW. (2009). Aurora B-mediated abscission checkpoint protects against tetraploidization. Cell. 136(3):473-84 (abstract)
 
(2008)
 
Patterson, GH., Hirschberg, K., Polishchuk, RS., Gerlich, D., Phair, RD., Lippincott-Schwartz, J. (2008). Transport through the Golgi apparatus by rapid partitioning within a two-phase membrane system. Cell. 133(6):1055-67 (abstract)
 
(2007)
 
Mora-Bermúdez, F., Gerlich, D., Ellenberg, J. (2007). Maximal chromosome compaction occurs by axial shortening in anaphase and depends on Aurora kinase. Nat Cell Biol. 9(7):822-31 (abstract)
 
(2006)
 
Gerlich, D., Hirota, T., Koch, B., Peters, JM., Ellenberg, J. (2006). Condensin I stabilizes chromosomes mechanically through a dynamic interaction in live cells. Curr Biol. 16(4):333-44 (abstract)
 
Gerlich, D., Koch, B., Dupeux, F., Peters, JM., Ellenberg, J. (2006). Live-cell imaging reveals a stable cohesin-chromatin interaction after but not before DNA replication. Curr Biol. 16(15):1571-8 (abstract)
 
(2004)
 
Bubulya, PA., Prasanth, KV., Deerinck, TJ., Gerlich, D., Beaudouin, J., Ellisman, MH., Ellenberg, J., Spector, DL. (2004). Hypophosphorylated SR splicing factors transiently localize around active nucleolar organizing regions in telophase daughter nuclei. J Cell Biol. 167(1):51-63 (abstract)
 
Dechat, T., Gajewski, A., Korbei, B., Gerlich, D., Daigle, N., Haraguchi, T., Furukawa, K., Ellenberg, J., Foisner, R. (2004). LAP2alpha and BAF transiently localize to telomeres and specific regions on chromatin during nuclear assembly. J Cell Sci. 117(Pt 25):6117-28 (abstract)
 
Giménez-Abián, JF., Sumara, I., Hirota, T., Hauf, S., Gerlich, D., de la Torre, C., Ellenberg, J., Peters, JM. (2004). Regulation of sister chromatid cohesion between chromosome arms. Curr Biol. 14(13):1187-93 (abstract)
 
Hirota, T., Gerlich, D., Koch, B., Ellenberg, J., Peters, JM. (2004). Distinct functions of condensin I and II in mitotic chromosome assembly. J Cell Sci. 117(Pt 26):6435-45 (abstract)
 
Leung, AK., Gerlich, D., Miller, G., Lyon, C., Lam, YW., Lleres, D., Daigle, N., Zomerdijk, J., Ellenberg, J., Lamond, AI. (2004). Quantitative kinetic analysis of nucleolar breakdown and reassembly during mitosis in live human cells. J Cell Biol. 166(6):787-800 (abstract)
 
Sumara, I., Giménez-Abián, JF., Gerlich, D., Hirota, T., Kraft, C., de la Torre, C., Ellenberg, J., Peters, JM. (2004). Roles of polo-like kinase 1 in the assembly of functional mitotic spindles. Curr Biol. 14(19):1712-22 (abstract)
 
(2003)
 
Gerlich, D., Beaudouin, J., Kalbfuss, B., Daigle, N., Eils, R., Ellenberg, J. (2003). Global chromosome positions are transmitted through mitosis in mammalian cells. Cell. 112(6):751-64 (abstract)
 
Gerlich, D., Ellenberg, J. (2003). Dynamics of chromosome positioning during the cell cycle. Curr Opin Cell Biol. 15(6):664-71 (abstract)
 
Gerlich, D., Ellenberg, J. (2003). 4D imaging to assay complex dynamics in live specimens. Nat Cell Biol. Suppl:S14-9 (abstract)
 
Gerlich, D., Mattes, J., Eils, R. (2003). Quantitative motion analysis and visualization of cellular structures. Methods. 29(1):3-13 (abstract)
 
(2002)
 
Beaudouin, J., Gerlich, D., Daigle, N., Eils, R., Ellenberg, J. (2002). Nuclear envelope breakdown proceeds by microtubule-induced tearing of the lamina. Cell. 108(1):83-96 (abstract)
 
Marhold, J., Zbylut, M., Lankenau, DH., Li, M., Gerlich, D., Ballestar, E., Mechler, BM., Lyko, F. (2002). Stage-specific chromosomal association of Drosophila dMBD2/3 during genome activation. Chromosoma. 111(1):13-21 (abstract)
 
Muratani, M., Gerlich, D., Janicki, SM., Gebhard, M., Eils, R., Spector, DL. (2002). Metabolic-energy-dependent movement of PML bodies within the mammalian cell nucleus. Nat Cell Biol. 4(2):106-10 (abstract)
 
(2001)
 
Gerlich, D., Beaudouin, J., Gebhard, M., Ellenberg, J., Eils, R. (2001). Four-dimensional imaging and quantitative reconstruction to analyse complex spatiotemporal processes in live cells. Nat Cell Biol. 3(9):852-5 (abstract)
 
J. Mattes, J. Fieres, J. Beaudoin, D. Gerlich, J. Ellenberg, R. Eils (2001). New Tools for Visualization and Quantification in Dynamic Processes: Applicati to the Nuclear Envelope Dynamics during Mitosis Proceedings of MICCAI. :1323-1325
 
(2000)
 
Eils, R., Gerlich, D., Tvaruskó, W., Spector, DL., Misteli, T. (2000). Quantitative imaging of pre-mRNA splicing factors in living cells. Mol Biol Cell. 11(2):413-8 (abstract)
 
Rustom, A., Gerlich, D., Rudolf, R., Heinemann, C., Eils, R., Gerdes, HH. (2000). Analysis of fast dynamic processes in living cells: high-resolution and high-speed dual-color imaging combined with automated image analysis. Biotechniques. 28(4):722-8, 730 (abstract)
 
(1998)
 
Leuzinger, S., Hirth, F., Gerlich, D., Acampora, D., Simeone, A., Gehring, WJ., Finkelstein, R., Furukubo-Tokunaga, K., Reichert, H. (1998). Equivalence of the fly orthodenticle gene and the human OTX genes in embryonic brain development of Drosophila. Development. 125(9):1703-10 (abstract)
 

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